Periodontal Ligament Stem Cells for Periodontal Regeneration
نویسندگان
چکیده
منابع مشابه
Periodontal Ligament Stem Cells
Millions of people experience consequential tooth loss related to irretrievable damage of the periodontium caused by deep caries, severe periodontal diseases or irreversible trauma, resulting in a decreased quality of life. Hence, dental scientists have focused much attention on tissue engineering techniques in an effort to address this condition. The periodontium is composed mainly of two soft...
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Periodontal regeneration is considered to be biologically possible but clinically unpredictable. In periodontitis, inflammation manifests clinically as loss of supporting periodontal tissues and regeneration of damaged tissue is the main goal of treatment. For decades, periodontists have sought to repair the damage through a variety of surgical procedures, and use of grafting materials and grow...
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The objective of this study was to investigate the advantages and feasibility of periodontal tissue regeneration using platelet-rich fibrin (PRF) combined with rat periodontal ligament stem cells (PDLSCs) for the first time. We first determined the effect of PRF on rat PDLSCs in vitro. We next conducted an in vivo study, in which a tissue engineering technique was performed to repair periodonta...
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It is astonishing how quickly the field of genetics has progressed in the past 50 years since the structure of the DNA molecule was first reported. Another major discovery that may revolutionize health care practices has been the derivation of human embryonic stem cells. These cells can be coaxed into developing specific tissues or organs to replace ones that have been lost to disease. The iden...
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Periodontitis is an inflammatory disease that causes pathological alterations in the tooth-supporting tissues, potentially leading to tooth loss. National surveys have shown that the majority of adults in the population suffer from moderate periodontitis, with up to 15% of the population being affected by severe generalized periodontitis at some stage in their lives (2, 17). The significant bur...
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ژورنال
عنوان ژورنال: Current Oral Health Reports
سال: 2015
ISSN: 2196-3002
DOI: 10.1007/s40496-015-0060-0